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Elusys Therapeutics : ウィキペディア英語版 | Elusys Therapeutics
Elusys Therapeutics is a biopharmaceutical company founded in Pine Brook, New Jersey in 1998. The company specializes in the development of antibodies for the treatment infectious diseases.〔(【引用サイトリンク】url=http://www.bloomberg.com/research/stocks/private/snapshot.asp?privcapId=92602 )〕 The antibodies are developed from protein complexes called heteropolymers which can bind to specific pathogens on one side and red blood cells on the other side. The pathogens will be dragged to the liver where they will be destroyed. The antibodies have a potential to be used for the treatments of many blood-borne diseases. Currently, the company focuses on the late-stage clinical trials of Anthim (Obiltoxaximab) to used for treatment and prevention of inhaled anthrax.〔(【引用サイトリンク】url=http://www.hoovers.com/company-information/cs/company-profile.ELUSYS_THERAPEUTICS_INC.7027d7663e00a047.html )〕 ==History== Ronald P. Taylor, a professor of biochemistry and molecular genetics at the University of Virginia developed protein complexes called heteropolymers that mimic the natural process of white and red blood cells in clearing out the disease off the bloodstream. The heteropolymers have specific binding that can bind to specific pathogens on one side and red blood cells on the other side. The red blood cells with the attached pathogens are delivered to the liver to be destroyed. In animal testing, the method can clear out pathogens within 2 hours. Taylor's research were partially funded by the National Institutes of Health and the Defense Advanced Research Projects Agency〔 Additional funding was arranged by Seed-One Ventures, a venture capital company, through the formation of Elusys to raise several million dollars. Jeff Wolf, the CEO of Seed-One, selected Stephen Sudovar who were former president of the U.S. division of Hoffmann-La Roche as the CEO of Elusys. Wolf also arranged to have Elusys' board of directors with prior experience from top global phamacuticle companies and Food and Drug Administration (FDA). As a startup, the company tested its first heteropolymers by using two chemically linked monoclonal antibodies for the treatment of lupus.
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